CD42b Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90248-50, BS90248-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P07359(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, ICC IHC FC

All Applications: WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Background: CD42a is a single-chain membrane glycoprotein that forms a noncovalent complex with CD42b. CD42b, also known as glycoprotein Ib a (GPIb a) is a membrane glycoprotein that is composed of a and b chains. The CD42b b chain is also designated CD42c, and is expressed on platelets and megakaryocytes. CD42a and CD42b are also present on platelets and mega-karyocytes, and the complex is a major component of the platelet surface. The complex acts as a receptor for von Willebrand's factor and as a von Willebrand's factor-dependent adhesion receptor.

Purification and Purity: Protein affinity purified.

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: CD42b polyclonal antibody detects endogenous levels of CD42b protein.

Bioworld Molecular Weight: 71 kDa (Predicted band size)

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining CD42b in Jurkat cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD42b antibody. Counter stained with hematoxylin.

Alternative Name: GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, CD42b, GP1BA, Antigen CD42b alpha, BDPLT1, BDPLT3, BSS, CD 42b, CD42b alpha, CD42B, CD42b antigen, DBPLT3, GLYCOCALICIN, Glycoprotein Ib (platelet) alpha polypeptide, Glycoprotein Ibalpha, GP Ib alpha, GP1B, GP1BA, GPIb alpha, GPIbA, MGC34595, Platelet glycoprotein Ib alpha chain, Platelet glycoprotein Ib alpha polypeptide, Platelet membrane glycoprotein 1b alpha subunit, VWDP,

Immunogen: Recombinant protein with human CD42b aa 130-310.

Conjugate: Unconjugated

Modification: Unmodified